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One KFF analysis estimates that roughly 36 million non-elderly Americans with employer coverage alone meet BMI criteria for a GLP-1, while only a small fraction are taking one today, which points to large latent demand constrained by cost

They also act on the appetite centers in the brain, significantly reducing hunger and what is often called food noise. The dual-action drug tirzepatide works on both GLP-1 and GIP receptors, often leading to even greater efficacy

PMID 20727946

Nat Rev Gastroenterol Hepatol 21 , 664666 (2024)

The World Health Organization (WHO) defines both overweight and obesity as abnormal or excessive fat accumulation that presents a risk to health

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