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Berberine can worsen gastrointestinal side effects when added to tirzepatide, particularly during the initial weeks of berberine introduction

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The authors declare that there are no other relationships or activities that might bias, or be perceived to bias, their work

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Results are expected in the 2027 to 2028 timeframe

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Disclosures Human subjects: Informed consent for treatment and open access publication was obtained or waived by all participants in this study

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