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Berberine can worsen gastrointestinal side effects when added to tirzepatide, particularly during the initial weeks of berberine introduction

The authors declare that there are no other relationships or activities that might bias, or be perceived to bias, their work

Results are expected in the 2027 to 2028 timeframe

Disclosures Human subjects: Informed consent for treatment and open access publication was obtained or waived by all participants in this study
