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The stepwise dose escalation is there to help your body adjust to the medication, minimizing potential side effects while optimizing its effectiveness
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Oveisi F, Gaetani S, Eng KT, Piomelli D
[DOI] [PubMed] [Google Scholar] Holst JJ, Bersani M, Johnsen AH, Kofod H, Hartmann B, Orskov C
doi: 10.1016/S0021-9258(18)35852-6 26 HolstJJ
Initial in vitro studies established its high potency and selectivity for ERR and ERR, with negligible activity at ERR and other nuclear receptor subtypes
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