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GLP-1 therapies reduce activity in brain reward centers, which lowers cravings and constant thoughts about food

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Generation of Gipr Syn/ mice and Glp1r Wnt1/ mice Mice expressing Cre recombinase driven by the synapsin promoter were purchased from Jackson Laboratories (JAX, stock no

Symptom Awareness : Patients learn to recognize symptoms of serious side effects, such as appendicitis (abdominal pain, nausea, vomiting), so they can seek prompt medical attention

Licensed injectable GLP-1 receptor agonists such as semaglutide and dulaglutide are available for appropriate patients through NHS prescribing

Abstract Introduction In type 2 diabetes (T2D), key barriers to optimal glycaemic control include lack of persistence with treatment, reduced medication adherence and therapeutic inertia