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When they first came to market for diabetes, they noticed a side effect was weight loss. A potentially complex treatment option The patient side of the equation can be complex, as some experts believe these medications, whether for diabetes or weight loss, may need to be taken throughout a persons life, as a direct treatment or maintenance therapy
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Furthermore, in 3T3-Ll adipocytes, GLP-1 stimulation improved insulin responsiveness by promoting increased glucose uptake and FA synthesis in adipose cells [80], possibly by CREB phosphorylation and ERK1/2 activation [81]
