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Obesity is the major risk factor for OSA, primarily due to the deposition of adipose tissue in the pharyngeal walls, tongue, and abdominal cavity, which increases upper airway collapsibility and reduces lung volume during sleep, predisposing individuals to airway obstruction [11, 12]

GLP-1RAs in nervous system In the nervous system, GLP-1 can decrease oxidative stress and inflammatory responses, potentially through reducing the generation of ROS and decreasing the expression of inflammatory cytokines

Weight loss has been long recognized as a disease-modifying therapy in IIH with patients being commonly recommended to lose 10% weight, although the amount of weight loss required to achieve disease remission remains unclear [1]

After PS matching, the mean diabetes duration in the GLP-1 RA group was 6.54.5 years, and the mean duration of GLP-1 RA treatment was 2.43.0 years

Twincretin drug Tirzepatide shows unmatched efficacy in weight loss and diabetes management

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