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Suchankova et al., 2023)

The Semaglutide Treatment Effect in People with Obesity and Heart Failure with Preserved Ejection Fraction and Diabetes Mellitus (STEP-HFpEF DM) trial demonstrated that semaglutide significantly reduced body weight and improved HF-related symptoms and physical limitations in people with obesity-related HF with preserved ejection fraction and type 2 diabetes mellitus [93]

By the time most adults reach their 40s and 50s, growth hormone levels have dropped significantly from their youthful peaks

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2013;8:e55447 Ropper AH, Shafran B

People on the maximum dose lost an average of 85 lb after 104 weeks, or slightly more than 30 percent of their starting body weight