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Divergence across payer type matters: Commercial patients adopt GLP1s earlier and often remain on monotherapy, while Medicare patients face stricter controls and higher comorbidity burdens

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Clinical Evidence: Retatrutide's Impressive Results In a recent phase 2 trial for obesity, retatrutide demonstrated remarkable efficacy: Up to 24.2% weight loss at 48 weeks with the highest dose, surpassing the weight loss seen with both semaglutide(15-17%)and tirzepatide (22.5%) at their respective highest doses