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(Bifidobacterium lactis BS01, Bifidobacterium breve BR03, Lactobacillus acidophilus LA02, Lactobacillus plantarum LP09, Lactobacillus rhamnosus LR06, Lactobacillus casei LC03, Bifidobacterium bifidum BB01, Streptococcus thermophilus YO8, Lactobacillus plantarum LP01, Lactobacillus rhamnosus LR05, Lactobacillus rhamnosus GG, Bifidobacterium longum BL03, Lactobacillus reuteri LRE02, Lactobacillus salivarius subsp. salivarius CRL1328, Bifidobacterium lactis BA05)

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While the overall frequency of liver enzyme elevations across the over 1,400 participant safety database of danuglipron is in-line with approved agents in the class, a single asymptomatic participant in one of the dose-optimization studies experienced potential drug-induced liver injury which resolved after discontinuation of danuglipron