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People who feel better emotionally are more likely to stick to their diet and exercise plans, which can support weight loss
10.1016/S0140-6736(05)67528-9 [EL 1

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While semaglutide showed sustained improvements in KCCQ-CSS, 6MWT, and weight loss compared to placebo, the durability of these effects beyond 52 weeks remains unproven

Nausea, headaches, constipation, diarrhea, fatigue, and stomach discomfort rank among the most common side effects