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Most people notice reduced appetite within the first 12 weeks

Retatrutides glucagon component appears particularly adept at addressing hepatic steatosis (fatty liver)

For type 2 diabetes, NICE guidance (NG28) recommends their use as second- or third-line therapy when metformin alone provides inadequate control, particularly in patients who would benefit from weight loss or where hypoglycaemia risk must be minimised

Its given as a once-weekly subcutaneous injection

China Market Trends China is an important market for oral GLP-1 agonists owing to its significant size of diabetic population and developing focus on breakthrough therapeutic options

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