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That observation ultimately reshaped the trajectory of the entire drug class, leading to obesity-specific formulations and, more recently, FDA approvals for additional chronic conditions

Medication is meant to work alongside changes to diet, activity, and behaviour, not to replace them

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Furthermore, Talay et al [56] have shown that proactive, personalized lifestyle coaching design significantly enhances patient engagement in semaglutide-supported programs, while another study by Talay et al [57] highlights the robust efficacy of tirzepatide-supported digital interventions [58]

Blood pressure lowering for prevention of cardiovascular disease and death: a systematic review and meta-analysis

SGLT2 Inhibitors: The Heart-Healthy Diabetes Treatment What are SGLT2 inhibitors