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However, with prolonged use, neuroendocrine adaptations and alterations in serotonergic regulation of appetite may lead to weight gain, as homeostatic mechanisms gradually adjust metabolic adaption over time
Roux-en-Y gastric bypass vs sleeve gastrectomy for obese patients with type 2 diabetes: a randomised trial
Regarding FDA approvals , Mounjaro is primarily approved for managing type 2 diabetes , although it has shown significant weight loss in studies
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[DOI] [PMC free article] [PubMed] [Google Scholar] 218.Maniscalco J.W., Rinaman L
The good news is that the body can get used to the medication
