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Structure of Peptibody From the perspective of anti-tumor antibody-drug conjugates (ADCs), ADCs connect cytotoxic cancer drug molecules with antibodies or antibody fragments

Biochem Pharmacol 164:3444 Pereira M, Jeyabalan J, Jorgensen CS, Hopkinson M, Al-Jazzar A, Roux JP, Chavassieux P, Orriss IR, Cleasby ME, Chenu C (2015) Chronic administration of glucagon-like peptide-1 receptor agonists improves trabecular bone mass and architecture in ovariectomised mice

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Skyrizi (risankizumab-rzaa) Disease area(s): Immunology Manufacturer(s): AbbVie 2024 Sales (USD): $11.72 billion Why it sold so well: AbbVies IL-23 inhibitor Skyrizi had remarkable growth in 2024, with global net revenues hitting $11 billion a 57.7% increase from 2023