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The SELECT trial was the first large, randomized study to show that a drug used for obesity could reduce cardiovascular disease, says Isaacs

It will also be important to establish whether lower doses continue to protect against weight regain, and which patients benefit most from switching to oral therapies

injection in the abdomen of the participant

This is not muscle wasting but part of a normal, adaptive remodeling process that restores balance between energy storage and energy use

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The difference between lyophilized and liquid peptide formats also affects storage timelines and preparation requirements