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We have found a significant and clinically meaningful reduction in ICP in the treatment arm as compared to the placebo arm both acutely and after 12 weeks of dosing

J Physiol [Internet]

The side effect profile is well-characterized: nausea, constipation , and gastrointestinal discomfort are the most common issues, typically resolving within the first 4-8 weeks

These data reflect exposure of 1,071 patients to RYBELSUS with a mean duration of exposure of 41.8 weeks

Davidson, A