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Hine J, Paterson H, Abrol E, et al

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Le Chatelier E, Nielsen T, Qin J, Prifti E, Hildebrand F, Falony G, Almeida M, Arumugam M, Batto J-M, Kennedy S, et al

Conclusions and future directions This review underscores the complex, bidirectional relationship between depression and diabetes, highlighting how each condition can exacerbate the other, complicating management and adversely impacting clinical outcomes

Beyond routine glucose and lipid panels, endocrine studies increasingly include microbiome profiling, bile-acid pools, and hepatokine/adipokine panels (FGF21, adiponectin) to explain shifts in substrate preference
