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December 20, 2023

doi: 10.1038/nm873

Metoclopramide to treat gastroparesis due to diabetes mellitus: a double-blind, controlled trial

Seven additional Phase 3 readouts are expected throughout 2026, including studies evaluating maintenance dosing at 4 mg (in addition to the 9 mg and 12 mg doses already tested)

We assessed validity and bias of QALY estimates by comparing differences in health state valuations, treatment priorities, and characteristics among respondents who did and did not complete the TTO

Observed side effects in research settings may include: Nausea Temporary digestive discomfort Reduced appetite Bloating Constipation Fatigue Headaches Injection-site irritation Proper reconstitution, sterile handling practices, consistent administration protocols, hydration, electrolyte support, and adequate protein intake are important considerations during research use