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Similarly, during menopause the depletion of the hormone estrogen can impact on the body's internal thermometer

It is plausible that retatrutide could offer similar benefits in this group given its potent metabolic effects, but this has not been directly studied

European Journal of Medicinal Chemistry

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The number on the scale may be acting like the 'canary in the coal mine.' It may be telling us about swallowing issues, loss of smell, gastrointestinal dysfunction, frailty, muscle loss, medication interactions or changes in cognition long before these problems become obvious