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Indications Hypertension first-line or add-on therapy Diabetic nephropathy especially in type 2 diabetes with proteinuria Heart failure for patients intolerant of ACE inhibitors Post-myocardial infarction reduces morbidity and mortality 3

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Semaglutide can be used safely by people with elevated cholesterol, and research shows GLP-1 receptor agonists may help improve lipid profiles alongside weight loss