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Some experts have even wondered whether the drugs systemic effects might slow cellular aging and prevent age-related chronic conditions, potentially making them the first true longevity drugs to hit the market

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The concerns below are less common but more serious and are the focus of many claims

It does not alter reproductive hormones through any primary mechanism

In the placebo-controlled studies, STEP 1 to STEP 4, AEs occurred in 88% to 96% of semaglutide patients and between 75% and 96% of placebo patients (Table 36 and Table 37)