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In the placebo condition, participants with obesity showed an imbalance common in overeating: their brain's reward areas lit up when the cue signaled the impending milkshake, indicating heightened craving or wanting, but their neural response during the actual tasting was blunted, indicating reduced liking

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If the solution turns cloudy, develops visible particles, or changes color at any point during the 28-day window, discard it immediately

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384, 2021, pp