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Subcutaneous fat gives our faces a youthful, rounded appearance

Buse JB, Wexler DJ, Tsapas A et al (2020) 2019 update to: Management of hyperglycaemia in type 2 diabetes, 2018

This activation triggers several physiological responses that can contribute to weight loss: Appetite regulation: Semaglutide helps reduce appetite and increase feelings of fullness (satiety)

VNS also altered the gut hormones releasing

By activating GLP-1 receptors in the central nervous system, semaglutide decreases hunger sensations and food cravings

Anti-inflammatory effects of exendin-4, a glucagon-like peptide-1 analog, on human peripheral lymphocytes in patients with type 2 diabetes