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Harvard Khetrapal, Afsaneh

Significant insulin-induced attenuation was observed predominantly in the occipital and prefrontal cortical regions, successfully localizing insulin-sensitive areas in the brain [107]

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In comparison to placebo, liraglutide treatment reduced the prevalence of NAFLD by two-thirds, the amount of fat in the liver by 44%, visceral adipose tissue by 18%, and body weight by 5.2 kg (5.6%) (199)

That triple agonism is generating intense interest in pre-clinical metabolic-research circles, where investigators are comparing it head-to-head against the dual agonist Tirzepatide and the GLP-1 mono-agonist Semaglutide

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