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Following these key discoveries about GLP-1, the next step was to turn it into a medication

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Both forms share class-typical side effects and safety considerations: Most common: Nausea, vomiting, diarrhea, constipation, abdominal pain, headache, dizziness, fatigue, and reflux

The 2025 KDIGO commentary highlights growing evidence that GLP-1RAs, particularly semaglutide, offer clinically meaningful kidney and CV protection in people with CKD, including those without DM