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[4] However, according to Harvard Health [5], there are potentially more serious side effects including pancreatitis, gastroparesis, bowel obstruction and gallstones

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For those of us with complex, multi-system conditions like MCAS or heritable connective tissue disorders, it may translate into improvements across multiple areas of dysfunction

Bupropion, an atypical antidepressant, and a dopamine/norepinephrine reuptake inhibitor, is believed to promote weight loss through its stimulatory effect on pro-opiomelanocortin (POMC) neurons in the arcuate nucleus of the hypothalamus

Trial data have shown decreases in serious cardiovascular complications, including cardiovascular mortality, nonlethal heart attacks, and nonfatal cerebrovascular accidents, among individuals with type 2 diabetes and pre-existing cardiovascular pathology or high cardiovascular risk [3,5,13,14,37]

Their broad metabolic effects make them valuable tools for tackling complex metabolic syndromes
