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BMJ 2026;392:e085304
Diet quality and movement patterns amplify semaglutide's effects beyond what the medication alone achieves
DPP-4 inhibitors (such as sitagliptin or linagliptin) provide a well-tolerated oral option with a low risk of hypoglycaemia, though their glucose-lowering efficacy is generally more modest than GLP-1 receptor agonists
