diabetes glp-1 agonist receptor agonists for individualized treatment of type 2 mellitus GLP-1 receptor agonists in the

59 Tirzepatide showed significant benefits on both co-primary endpoints, namely adjudicated death from cardiovascular causes or worsening HF events (HR 0.62

Clinical utility of cardiovascular risk scores for identification of people with type 2 diabetes more likely to benefit from either GLP-1 receptor agonist or SGLT2 inhibitor therapy

Semaglutide has a favorable safety profile with low hypoglycemia risk when used for weight loss (unlike older diabetes medications)

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Studies concerning indirect mechanisms linking GLP-1 RAs, to coronary events are not included

3 Future studies are needed to determine whether this class of medications inhibits progression from nonexudative to neovascular or late atrophic stages of AMD