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Enteroendocrine L-cell derived peptide hormones, notably glucagon-like peptide-1 (GLP-1) and glucagon-like peptide-2 (GLP-2), have become important targets in the treatment of type 2 diabetes, obesity and intestinal diseases

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For the more than 48 million Americans with substance use disorders, including a disproportionate share of veterans, GLP-1 drugs are not yet an approved addiction treatment

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The is 2013 - 2016: It all started with Novartis developing Bimagrumab and receiving an FDA breakthrough designation in August 2013 for sporadic inclusion body myositis.In 2016, it failed a Phase IIb/III trial