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GLP-1s like Wegovy and Zepbound have both been associated with increased weight loss during menopause

Published January 10, 2026

However, recent developments online, and trending terms such as : Ozempic face, meaning a gaunt, drawn facial sagging caused by weight loss, Ozempic personality referring to side effects such as anxiety, depression and anhedonia, and Ozempic crazy, which suggests people are obsessing over the drug (to the point that there is a shortage for the intended diabetic application), suggest a shift in sentiments towards these substances

10.1038/nri3495 4 ChengL.HuY.LiY

Plaintiffs allege that the drug, prescribed for type 2 diabetes and weight loss, caused serious gastrointestinal complications, including gastroparesis

Additionally, reduced appetite and lower overall fluid intake during treatment can compound the drying effect, as your mouth produces less saliva when your body expects less food