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Big news: The World Health Organization (WHO) has released its first global guideline on using GLP-1based medicines to treat obesity redefining obesity as a chronic, relapsing disease that deserves long-term care

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Medications like semaglutide, tirzepatide, liraglutide, and others are defined as GLP-1 meds, and they've revolutionized weight reduction

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Methods We administered male rats with intraperitoneal (i.p.) or intracerebroventricular (i.c.v.) GLP-1R agonist (exendin-4) or antagonist (exendin-9-39) followed by in vivo determination of CSF dynamics

Are you starting or currently using a GLP-1 medication