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Skin-supporting peptides and skin tightening compounds like GHK-Cu can address the cosmetic concerns that sometimes accompany significant weight loss during menopause

Stock solutions of test compounds that are water soluble were made up at 20 times the final assay concentration in buffer (including glucose, GEP44, GEP12, exendin-4, PYY 1-36 and insulin)

The magnitude of difference reflects each drug's biological action

Neuen BL, Heerspink HJL, Vart P, et al

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