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To assess changes in prescribing after the FDAs November 2025 removal of boxed warnings from several hormone therapies, we also compared prescribing rates between November 2025 and May 2026

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Expiries2026 abroad, 2031 in the U.S.open doors

The authors conclude: In the STEP TEENS trial, treatment with semaglutide 2.4 mg once weekly for 68 weeks was associated with a significant reduction of levels of the liver enzyme alanine aminotransferase compared with placebo. Dr Weghuber adds: Fatty liver disease is the most frequent liver disease in adolescents with no drug therapy currently available

Research shows that while initial weight loss is achievable, maintaining it is difficult, with one analysis finding that more than half of lost weight is regained within two years, and over 80% within five years