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They also require multiple doctors visits and tedious insurance forms

Jastreboff, AM, et al

However, research on GLP-1 and tirzepatide therapy suggests a target range of 1.2 to 1.6 grams per kilogram body weight optimizes muscle retention during rapid weight loss

Clinical trials paired semaglutide with reduced-calorie diets (approximately 500 calories below maintenance) and 150 minutes of weekly physical activity

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