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A few patients, particularly repeat ones, have described health complications

Insulin resistance in multiple tissues in patients with type 1 diabetes mellitus on long-term continuous subcutaneous insulin infusion therapy

Naproxen is a nonsteroidal anti-inflammatory drug (NSAID), which works by reducing the production of prostaglandinschemicals in the body that signal pain and inflammation

Sulfur-containing amino acids in protein break down more slowly in this environment, creating hydrogen sulfide gas that produces the characteristic rotten-egg smell

Preexisting diabetes and pregnancy: an Endocrine Society and European Society of Endocrinology Joint Clinical Practice Guideline

However, challenges related to cost, solubility, stability, immunogenicity and bioavailability persist when developing these new therapeutics