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Its also important to clear up a common misconception between compounded and generic medications

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Your healthcare provider may recommend baseline assessment of reflux symptoms and consider concurrent acid-suppressive therapy with proton pump inhibitors if needed

Less fluid in the gut means: Less lubrication Firmer stools Slower transit Dehydration also concentrates electrolytes like calcium, which can have constipating effects

Of note, compounded medications are not approved for safety nor efficacy by the FDA

Summary: Retatrutide may indirectly reduce vitamin B12 levels by substantially lowering dietary intake, though no direct pharmacological effect on B12 absorption has been confirmed