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Description
The original development partner, Janssen Pharmaceuticals, has handed back the license for efinopegdutide to the original developer, Hanmi Pharmaceutical, but the license has been taken up by Merck to be developed as a once weekly treatment for NAFLD

It is approved specifically for chronic weight loss and for moderate to severe obstructive sleep apnea in adults with obesity

Even with insurance, many patients face hurdles like prior authorizations or step therapy

Some cardiovascular benefits may be partly mediated by improved glycemic control and weight loss

These results suggest that mild to moderate hyperglycemia is required for the insulinotropic effect of GIP in nondiabetic subjects, acting as a mechanism to prevent reactive hypoglycemia following the consumption of fatty foods

[DOI] [PMC free article] [PubMed] [Google Scholar] 26.Centers for Medicare and Medicaid Services
