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Methods Forty-five subjects, categorized by baseline renal status, i.e

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GLP-1 receptor agonists do not have direct effects on bladder function or structure, as GLP-1 receptors are not significantly expressed in bladder tissue

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A phase 3 trial found the once-daily pill orforglipron lowered blood sugar and body weight more than oral semaglutide in adults with type 2 diabetes.

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