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Over the four-year period, the percentage of female patients with a semaglutide or tirzepatide prescription who also had PCOS increased from 4.6% in 2021 to 5.7% in 2025, representing a 23.9% relative increase

We outline the most significant developments, the theories supporting these enforcement actions and the implications for research sites and other clinical operators

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NICE guidelines (NG28) recommend GLP-1 receptor agonists for type 2 diabetes based on individual patient factors, including cardiovascular risk, and not strictly as second- or third-line therapy after metformin failure

Metformin versus sulphonylureas for new onset atrial fibrillation and stroke in type 2 diabetes mellitus: a population-based study

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