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Description

The UK Medicines and Healthcare products Regulatory Agency (MHRA) has today approved a new indication for Wegovy (semaglutide) to reduce the risk of overweight and obese adults suffering serious heart problems or strokes.

Rapid weight loss with GLP1 receptor agonists can come at the cost of skeletal muscle, potentially undermining metabolic and functional outcomes

Why are people microdosing weight-loss drugs

Mechanistic hypotheses include reduced leptin-driven T-helper (Th)1/Th17 activity, improved adipokine balance, and modulation of gut-thyroid axis pathways

Methods A retrospective study was conducted using electronic medical records from 2014 to 2019 for adults with T2D at the Valencia Clnico-Malvarrosa Department of Health (Valencia, Spain)