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do glp 1 drugs cause muscle loss Study finds GLP-1 receptor agonists target fat over for weight Hidden Risks of GLP-1 Inhibitors:
Description
It neutralizes the stomach acid long enough for the GLP-1 to be absorbed into the bloodstream, retaining higher bioavailability, though still not as high as injectable GLP-1s

Compared with the NC group, the liver TG level, total liver TC level, and liver weight of the OC group were increased
The exenatide analogue AC3174 attenuates hypertension, insulin resistance, and renal dysfunction in Dahl salt-sensitive rats

Specifically, there are concerns that GLP-1 agonists may cause a loss of muscle mass and function

Intra 4th-ventricular administration of exendin (939) or lesions of the AP also block food intake inhibition by GLP-1 infused into the hepatic portal vein (HPV) [261], suggesting that high levels of circulating GLP-1 inhibit eating at least in part by acting on the hindbrain

You want to lose fat while retaining muscle