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[DOI] [PMC free article] [PubMed] [Google Scholar] 49.Vos M.B., Abrams S.H., Barlow S.E., et al
Everyone in oncology is grappling with how to assess clinical relevance, says Hartmann, and there will be increasing pressure to introduce new drugs earlier in treatment lines for ethical reasons, but this will make overall survival harder to assess for a certain agent and puts more emphasis on wider quality-of-life benefits and surrogate measures of possible success
The essential companion product while on GLP- 1 therapy
Myocardial Metabolism The GLP-1 agonists increase myocardial glucose uptake and change the metabolic pathways toward glucose oxidation by increasing the energy efficiency of the heart during ischemia or failure [9]
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