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Garvey WT, Batterham RL, Bhatta M, Buscemi S, Christensen LN,Frias JP, et al

7 As the first approved dual agonist targeting both GLP-1 and glucose-dependent insulinotropic polypeptide (GIP) receptors, tirzepatide demonstrated weight loss exceeding 20% in its pivotal trials, establishing a new therapeutic ceiling

[DOI] [PMC free article] [PubMed] [Google Scholar] 64.Imbernon M, Saponaro C, Helms HC, Duquenne M, Fernandois D, Deligia E, et al

For people who are on a GLP-1 already, they would be assessed as of the day they started GLP-1 therapy , not where they stand today

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TCF7L2 Variants Are Associated with Increased Proinsulin/Insulin Ratios but Not Obesity Traits in the Framingham Heart Study. Diabetologia, vol