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One of the advantages of using the two in tandem is to alleviate some of the side effects that semaglutide GLP-1 can bring on, such as nausea, fatigue, or stomach discomfort
Lincoff AM, Brown Frandsen K, Colhoun HM (2023) Semaglutide and Cardiovascular Outcomes in Obesity without Diabetes
Current clinical evidence shows no direct pharmacokinetic interaction between these two compounds, but combination therapy requires individualized assessment and close provider monitoring to optimize outcomes

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