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The increase in oestrogen levels is attributed to an increase in the activity of aromatase within adipose cells particularly those seen in the breast tissue [32, 76]
Mitochondrial biogenesis transcripts (PGC-1 targets), fatty acid oxidation genes, and DDIT4 an acute aerobic exercise gene were upregulated within hours of a single IP dose (Billon et al., ACS Chem Biol 2023, PMID 36988910)
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Some nicotine replacement therapies or sleep aids can also contribute to vivid dreaming
These small changes are the earliest visible signs of the transformation that will accelerate dramatically over the coming months
