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If symptoms persist beyond 68 weeks despite lifestyle modifications, contact your PlexusDx provider about potential solutions: temporary dose stabilization at your current level (rather than titrating further), brief dose reduction, or a switch to a different GLP-1 or GLP-1/GIP medication if cold sensitivity severely impacts quality of life

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These improvements may prove critical for women with PCOS should GLP-1 medications obtain the appropriate authorisation, as managing weight and insulin resistance can significantly improve overall health and fertility

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