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The American Diabetes Association 2026 Standards of Care provides guidance on selecting appropriate glucose-lowering therapy based on cardiovascular, kidney, and metabolic considerations

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We describe the drugs and months with the highest rates of switching
Stenberg E, Nslund E (2023) Major adverse cardiovascular events among patients with type-2 diabetes, a nationwide cohort study comparing primary metabolic and bariatric surgery to GLP-1 receptor agonist treatment

Studies on rat knee sections showed GLP-1RA in the articular chondrocytes
6 Additionally, insulin resistance may lead to dopamine degeneration and disrupted glucose metabolism in several brain regions, further exacerbating the progression of PD
