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[88] In March 2026, the CHMP recommended granting a conditional marketing authorization for Kayshild (semaglutide), a GLP-1 receptor agonist for the treatment of non-cirrhotic metabolic dysfunction-associated steatohepatitis (MASH) with liver fibrosis, a serious disease where fat deposits accumulate in the liver causing inflammation

We note that not every nucleus distal to the GLD-1 boundary was arrested in M-phase in some gonads but these few nuclei were included in the distal pool counts

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For example, a typical schedule might look like this: Initial Dose: 0.25 mg once weekly for the first four weeks