glp-1 obesity drug updates today The revolution: What UAB researchers are discovering about how these drugs work GLP-1 anti-obesity drugs lead to

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Animal models show that GLP-1 drugs improve memory, reduce neural apoptosis, and increase synaptic density

National Kidney Foundation

However, researchers began to notice that these drugs were also effective in suppressing appetite, helping promote weight loss

Liraglutide (Saxenda): The Original Weight Loss GLP-1 Liraglutide was the first GLP-1 receptor agonist to receive FDA approval specifically for chronic weight management, doing so in 2014 under the brand name Saxenda

Compared with GLP-1 RAs, tirzepatide 5, 10 and 15 mg reduced HbA 1c levels by 3.22 mmol/mol (0.29%), 7.11 mmol/mol (0.65%) and 10.06 mmol/mol (0.92%), respectively (Fig