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196 The refined model successfully described the pharmacokinetic profiles of the affected drug, atorvastatin acid and lactone, after dulaglutide administration in Simcyp TM (Certara UK Limited, Sheffield, United Kingdom)

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Cloning of rat and human pancreatic GLP-1R cDNA documented that ligand-induced activation of a single unique GLP-1R increases intracellular levels of cAMP and also that GLP-1, but not glucagon, GIP, VIP, or secretin, activates GLP-1R [[360], [361], [362], [363], [364]]

doi: 10.1038/379069a0 27 Tang-ChristensenMLarsenPJGokeRFink-JensenAJessopDSMollerMet al

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One involves the neurocircuitry of addiction